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CHAPSO

(Detergent zwitterionic)


S113   (3-[3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate, 99+%
[ 82473-24-3 ]   f.w.: 630.9 daltons

CHAPSO is a zwitterionic detergent that solubilizes proteins in their native state. It has a higher solubilty than CHAPS.



Quantity Price  
2gm $38.00
5gm $76.00
10gm $145.00
25gm $325.00
100gm $1250.00
Download***Certificate of Analysis***


Zwitterionic detergent. Higher solubilty than CHAPS. Solubilizes membrane proteins in their native state. Solubilizes opiate receptor to a state exhibiting reversible binding of opiates. Purity > 99% by TLC. Conductivity < 50 micromhos in 10% solution.

  1. L.M. Hjelmeland, Proc. Natl. Acad. Sci. USA, 77, 6368 (1980 
  2. W.F. Simonds, G. Koski, R.A. Streaty, L.M. Hjelmeland, W.A. Klee, Proc. Natl. Acad. Sci. USA, 77, 4623 (1980) 
  3. D.S. Liscia, T. Alhadi, B.K. Vonderhaar, J. Biol. Chem., 257, 9401 (1982) (1991) 
  4. W. Gaertner, D. Ulrich, K. Vogt, Photochem. Photobiol., 54, 1047 
  5. H.H. Hassanain, W. Dai, S.L. Gupta, Anal. Chem., 213, 162 (1993) 
  6. W. Hu, T. Takeuchi, H. Haraguchi, Anal. Chem., 65, 2204 (1993) 
  7. P. Banerjee, J.B. Joo, J.T. Buse, G. Dawson, Chem. Phys. Lipids, 77, 65 (1995)
  • CMC (H2O): ~ 8 mM (0.50%)
  • Aggregation Number (H2O): ~ 11
  • Purity: ? 99% by HPLC analysis.
  • pH (1% solution): 5-8
  • Solubility in water:  0.5M (31.5%)
  • Conductance (0.5M solution): < 100 S
  • Percent fluorescence due to a 0.1% detergent solution at 345 nm: < 10
  • Absorbance of a 1% detergent solution: 340 nm: < 0.02 280 nm: < 0.04 260 nm: < 0.06