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Bolton Hunter SULFO SHPP

(Iodination Reagent)

I103   N-Sulfosuccinimidyl-3-(4-hydroxyphenyl)propionate
  f.w.: 365.3 daltons

Sulfo SHPP is the water soluble Bolton Hunter reagent. It conjugates tyrosine like functional groups to primary amines to increase the number of tyrosyl groups that can be iodinated by iodine-125 labeling procedures.

Quantity Price  
1gm $93.60
5gm $442.00

Water soluble Bolton Hunter iodination reagent. Reacts with N-terminal amino groups at pH 8.5. Iodinate before or after coupling to molecule of interest.
1.Thompson, J.A., Lau, A.L. and Cunningham, D.D. (1987). Selective radiolabeling of cell surface proteins to a high specific activity. Biochem. 26, 743-750.
2.Thirkell, D., Myles, A.D. and Russell, W.C. (1989). Serotype-8 and serocluster-specific surface-expressed antigens of Ureaplasma urealyticum. Infection and Immunity 57, 1697-1701.
• Also known as water soluble Bolton Hunter reagent, sulfosuccinimidyl-3 -(4-hydroxypheynyl) propionate
• Iodinate before or after coupling Sulfo SHPP to the molecule of interest
• Useful for introducing tyrosyl groups on proteins sensitive to small amounts of organic solvent
• Useful for labeling cell surfaces without exposing the cells to membrane permeable solvents