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Sulfobetaine 14

(Detergent zwitterionic)


S122   N-Tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate, 99+%
[ 14933-09-6 ]   f.w.: 363.6 daltons

A synthetic zwitterionic detergent, which unlike other amphoteric surfactants, retains its zwitterionic character over a broad pH range.



Quantity Price  
2gm $42.00
5gm $89.10
10gm $163.30


A synthetic zwitterionic detergent, which unlike other amphoteric surfactants, retains its zwitterionic character over a broad pH range. This property is attributed to the presence of both a strongly basic quaternary ammonium ion and an acidic sulfonate ion of equal strength. This ionic balance presumably prevents irreversible binding to either anionic or cationic compounds.

  1. Brito, R. M. M. and Vaz, W. L. C. (1986) Anal. Biochem. 152, 250-255. 
  2. LeMaire, M., Champeil, P., and Moller, J. V. (2000) Biochimica et Biophysica Acta 1508, 86-111.
  • CMC (H2O): ~ 0.16 mM
  • CMC (10 mM Phosphate, pH 7.5): 0.2 mM(2) (0.007%)
  • Aggregation Number (H2O)(3): ~ 83-130
  • Purity:  98% pure by HPLC analysis.
  • pH (1% solution): 5-8
  • Solubility in water at 20°C: 30%
  • Conductance (10% solution): < 70 micromhos
  • Percent fluorescence due to a 0.1% detergent solution at 345 nm: < 10 •Absorbance of a 1% detergent solution: 340 nm: < 0.02 280 nm: < 0.04 260 nm: < 0.06 225 nm: < 0.1