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DST

(Protein Crosslinker homobifunctional)


CL108   Disuccinimidyltartrate
  f.w.: 344.2 daltons

DST is a water soluble crosslinker that contains amine reactive NHS ester ends around a 4-atom spacer arm, whose central diol can be cleaved by periodate oxidation.



Quantity Price  
50mgm $72.00
100mgm $136.00
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Spacer arm 6.4 angstroms. Cleavable homobifunctional reagent. Can be cleaved with 0.015M sodium periodate or other oxidizing agents.

  1. Farries, T.C. and Atkinson, J.P. (1989). Biosynthesis of properdin. J. Immunol. 142, 842-847. 
  2. Park, L.S., Friend, D., Gillis, S. and Urdal, D.L. (1986). Characterization of the cell surface receptor for a multi-lineage colony-stimulating factor (CSF-2 ). J. Biol. Chem. 261, 205-210.
  • DST is soluble in water, DMSO or DMF at a concentration of ~10mM (3mg/ml)
  • Cleavable by sodium meta-periodate
  • Ideal for applications in which crosslinking cleavability is desired without disturbing protein S-S bonds
  • Reactive groups: NHS ester (homobifunctional)
  • Reactive toward: amino groups