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CHAPS

(Detergent zwitterionic)


S112   (3-[3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate, 99+%
[ 75621-03-3 ]   f.w.: 614.9 daltons

CHAPS is a zwitterionic detergent that solubilizes proteins in their native state. It has all the advantages of sulfobetaine containing detergents - hydrophobic, bile salt, and anionic detergents in a single molecule. Has a low molecular weight and high cellular micellar concentration. Product can be removed from protein solutions with a detergent removing gel or by dialysis.



Quantity Price  
2gm $13.50
5gm $30.00
10gm $58.00
25gm $145.00
100gm $480.00
Download***Certificate of Analysis***


Zwitterionic detergent. Has all the advantages of sulfobetaine containing detergents-hydrophobic, bile salt, and anionic detergents in a single molecule. Has a low molecular weight and high cellular micellar concentration. Product can be removed from protein solutions with a detergent removing gel or by dialysis. Purity > 99% by HPLC. Conductivity < 25 micromhos in a 10% solution.

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  11. Wetlaufer, D. B., et al, Protein Sci, 4, 1535 (1995)
  • CMC (H2O): ~ 8 mM (0.49%)
  • Aggregation Number (H2O): ~ 10dn/dc (H2O): 0.1323 mL/g
  • Purity:  98% pure by HPLC analysis.
  • pH (1% solution): 5-8
  • Solubility in water:  0.5M
  • Conductance (0.5 M solution): < 200 ?S
  • Absorbance of a 1% detergent solution: 340 nm: < 0.05 280 nm: < 0.1 260 nm: < 0.2