GMBS

(Protein Crosslinker heterobifunctional)

CL231

N-(beta-Maleimidobutyrloxy)succinimide

CAS#: [ 80307-12-6 ]

Formula Weight: f.w.: 280.2 daltons

GMBS is an amine to sulfhydryl crosslinker that contains NHS ester and maleimide reactive groups at opposite ends of a short spacer arm (7.3 angstroms).

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Pricing & Ordering

Quantity Price Action
50mgm + $106.00
100mgm + $200.00
Product Documents
Certificate of Analysis


Spacer arm 6.8 angstroms. Heterobifunctional crosslinker. Analog of MBS, less immunogenic than SMCC. Non cleavable. Low potential for eliciting an immune response ensuring that their primary response to the antigen-carrier protein conjugate is not diluted by a response against a determinant on the crosslinker.

    

  1. Chrisey, L.A., et al. (1996). Nucleic Acids Res. 24(15), 3031-3039. 
    2. 

  2. Fujiwara, K., et al. (1988). Sandwich enzyme immunoassay of tumor-associated antigen sialosylated Lewis (x) using beta-D-galactosidase coupled to a monoclonal antibody of IgM isotype. J. Immunol. Meth. 112, 77-83.
    3. 

•GMBS has a low potential for eliciting an immune response, ensuring that the primary response is to the antigen-carrier protein conjugate and not against a determinant on the crosslinker •Less immunogenic than SMCC •Reactive groups: NHS ester and maleimide •Reactive toward: amino and sulfhydryl groups