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Biotinylation Reagents                  Sulfo NHS SS Biotin

the disulfide bond in the spacer arm is cleavable using reducing agents such as TCEP and DTT

B105    Sulfosuccinimidyl-2-(biotinamido)ethyl-1,3-dithiopropionate

                     f.w.:606.7daltons

                    Spacer arm 24.3 angstroms                 

  • Sulfo NHS SS biotin biotinylates, amino acids, peptides or proteins under mild conditions

  • Ideal for reversible biotinylation

  • Cleavable water soluble analog to NHC LC Biotin

  • Soluble in water

    unit price
    50mgm $85.50
    100mgm $161.50
      Download Certificate of Analysis
    Sulfo NHS SS Biotin has a spacer arm 24.3 angstroms long. It is a cleavable biotinylation reagent. Sulfo NHS SS Biotin is a water soluble biotinylation reagent that is reversible. It is useful for extracting non covalently associated proteins from complex physiological mixtures under mild isolation conditions. Soluble in water.
  • Forms stable amide bonds

  • Extended spacer arm reduces steric hindrance

Sulfo NHS SS Biotin







We manufacture these products so bulk quotations are always available with substantial savings.

Each product is accompanied with a certificate of analysis.

 Sulfo NHS SS Biotin References:

  1. Shimkus, M., et al, Proc. Natl. Acad. Sci., 82, 2593-2597 (1985).
  2. Duhamel, R.C., Johnson, D.A., J. Histochem. Cytochem., 33, 711-714 (1985).
  3. Gottardi, C.J., et al, Am. J. Physiol., 268(2), F285-F295 (1995).
  4. Soukup, G.A., et al, Bioconjugate Chem., 6, 135-138 (1995)
  5. Daniels, G.M., Amara,S.G., Methods Enzymol., 296, 307-318 (1998).
  6. Huh, K.H., Wenthold, R.J.,  J. Biol. Chem., 274, 151-157 (1999).
  7. Trotti, D., et al, J. Biol. Chem., 276, 576-582 (2001).