Protein Crosslinkers SPDP
Heterobifunctional
CL210 Succinimidyl-3-(2-pyridyldithio)propionate
f.w.:312.4daltons
Spacer arm 6.6 angstroms
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introduces thiol groups into a variety of proteins
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primary amine and sulfhydryl reactive
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cleavable
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treatment with DTT releases 2-pyridylthione and a mercaptopropionyl modified amine
| unit | price |
| 50mgm | $99.90 |
| 100mgm | $188.70 |
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SPDP References:
1. Cumber, J.,A., et al., Methods Enzymology, 112, 207-224 (1985).
2. Gordon, R.D., et al., PNAS, 84, 308-312 (1987).
3. Carlsson, J. et al., J. Biochem., 173, 723-737 (1978).