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Protein Crosslinkers                                    SMCC

Heterobifunctional

CL206    Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate

                    [ 64987-85-5 ]    f.w.:334.3daltons

                    Spacer arm 11.6 angstroms                 

• Cyclohexane bridge gives stability to the maleimide reactive group

• Useful for enzyme labeling of antibodies

• Soluble in acetonitrile and DMF

• Purity >98% by TLC

We manufacture these products so bulk quotations are always available with substantial savings.

Each product is accompanied with a certificate of analysis.

SMCC References

1. Uto, I., et al. . J. Immunol. Methods 138, 87-94 (1991).
2. Bieniarz, C., et al. , Bioconjug. Chem. 7, 88-95 (1996).
3. Chrisey, L.A., et al. , Nucleic Acids Res. 24(15), 3031-3039 (1996).
4. Kuijpers, W.H., et al., Bioconjug. Chem. 4(1), 94-102  (1993).
5. Brinkley, M.A. , Bioconjugate Chem. 3, 2-13 (1992).
6. Hashida, S., et al.,  in the hinge. J. Appl. Biochem. 6, 56-63  (1984)..
7. Mattson, G., et al.,  Molecular Biology Reports 17, 167-183 (1993).
8. Partis, M.D., et al., J. Protein. Chem. 2, 263-277  (1983) .
9. Samoszuk, M.K., et al., Immunoconjugates and Radiopharmaceuticals 2, 37-45 (1989).
10. Yoshitake, S., et al., J. Biochem. 92, 1413-1424  (1982) .