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Biotinylation Reagents                         NHS LC Biotin

NHS LC Biotin has an extended spacer arm and reduces steric hindrance when binding several biotinylated molecules to one avidin complex.

B104    Succinimidyl-6-(biotinamido)hexanoate

                     [ 72040-63-2 ]    f.w.:455.5daltons

                    Spacer arm 22.4 angstroms                 

  • NHS LC biotin biotinylates, amino acids, peptides or proteins under mild conditions

  • Penetrates cell membranes

  • Less water soluble than Sulfo NHS LC Biotin

  • Dissolve in DMSO or DMF before use

  • Forms stable amide bonds




NHS LC Biotin

We manufacture these products so bulk quotations are always available with substantial savings.

Each product is accompanied with a certificate of analysis.

 NHS LC Biotin References:

  1. Burgess, T.L., et al, J. Biol. Chem., 270(32), 19188-19196 (1995).
  2. Gretch, D.R., et al, Anal. Biochem., 163, 270-277 (1987).
  3. Ying, S.C., et al, J. Immunol., 143(1), 221-228 (1989).
  4. Herwald, H., et al, J. Biol. Chem., 270(24), 14634-14642 (1995)
  5. Jans, D.A.., , et al, J. Biol. Chem., 265(24), 14599-14605 (1990).
  6. Schumacher, T.N., et al, Science, 271, 1854-1857 (1996).
  7. Tang, A., et al, Nature, 361, 82-85 (1993).
  8. Chui, N.H, et al, Clin. Chem., 45, 1954-1959 (1999).
unit price
50mgm $81.00
100mgm $153.00
  Download Certificate of Analysis
NHS LC Biotin has a spacer arm 22.4 angstroms long. It ios a biotinylation reagent. NHS LC Biotin reacts with primary amines to biotinylate proteins under mild conditions. Purity >94% by TLC. Soluble in dimethylsulfoxide.