GC Diagnostic Reagents MTBSTFA with 1% T-BDMCS
Silylation derivatization reagent mixtures with references
GC115 N-Methyl-N-(tert-butyldimethylsilyl)trifluoroacetamide, with 1% tert-Butyldimethylchlorosilane, 99+%
[ 77377-52-7 ] f.w.:241.3daltons
b.p. 168-170°; d. 1.023
- Derivatizes hydroxyl, carboxyl, thiol and primary and
secondary amines
- Typical yields are >96%
- Provides TBDMCS ethers that are 104 times more stable to
hydrolysis than TMS ethers
- Reaction byproducts are neutral and volatile
- Derivatives have a high molecular concentration at M-57
- Silylating potential increased by adding 1% TBDMCS
- MBTSTFA and MBTSTFA + 1% TBDMCS convert hydroxyls, carboxyls,
thiols and primary and secondary amines to TBDMS (tert-butyldimethylsilyl)
derivatives, which are 10,000 times more stable than TMS
ethers1. The reaction requires only 5 to 20 minutes to complete,
and the by-products are neutral and volatile, preventing
clogging of chromatography instruments. The addition of 1%
TBDMCS acts as a catalyst, improving performance compared to
MBTSTFA alone.
| unit | price |
| 5gm | $69.00 |
| 10gm | $99.00 |
| 25gm | $130.00 |
The products are packaged in hypovials with septum inserts for ease in sampling and use.
We manufacture these products so bulk quotations are always available with substantial savings.
Each product is accompanied with a certificate of analysis including the GC chromatogram from QC