Protein Modification Reagents DTT
A water soluble reagent that reduces disulfide bonds.
| unit | price |
| 5gm | $30.00 |
| 10gm | $38.00 |
| 25gm | $48.00 |
| 50gm | $60.00 |
| 100gm | $99.00 |
M112 (D,L)-1,4-Dithiothreitol, 99.5+%
[ 27565-41-9 ] f.w.:154.3daltons
m.p. 42-44°C
- DTT quantitatively reduces disulfides
- Protective reagent for sulfhydryl groups
- DTT promotes proteins to unfold and maximize bonding
- phone: 978 922 9446
- fax: 978 922 1666
- email: sales@soltecventures.com
Cleland's reagent, also known as dithiothreitol or DTT is a water soluble protective reagent for sulfhydryl groups. It is capable of maintaining monothiols completely in the reduced state and reduces disulfudes quantitatively. Since its introduction in 1964 by Professor Cleland it has gained widespread acceptance as the reagent of choice for the protection of sulfhydryl groups. DTT readily permeates cell membranes. therefore DTT protects protein sulfhydryls allowing enzyme activity to be restored due to the oxidation of sulfhydryl groups in vitro.
We manufacture these products so bulk quotations are always available with substantial savings.
Each product is accompanied with a certificate of analysis.
DTT references:
1. Cleland, W.W., Biochemistry, 3, 480-482 (1964)
2. Lauriault, V.V.M., O'Brien, P.J., Mol. Pharmacol., 40, 125 (1991).
3. Klonne, D.R., Johnson, D.R., Toxicol. Lett., 42, 199 (1988).