Purified Detergents CHAPS
The purified zwitterionic detergent CHAPS to solubilize proteins is available in bulk quantities.
S112 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate, 99+%
| unit | price |
| 2gm | $13.50 |
| 5gm | $30.00 |
| 10gm | $58.00 |
| 25gm | $145.00 |
| 100gm | $480.00 |
[ 75621-03-3 ] f.w.:614.9daltons
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Zwitterionic detergent
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CHAPS solublizies proteins in their native state
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Purity >99% by TLC
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Conductivity <50 mircomhos in 10% aqueous solution
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Critical micellar concentration CMC (water) ca. 8mM (50%)
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Aggregation number (water) ca. 10
CHAPS has a cholic acid and sulfobetaine moiety in the structure. The low background absorbance in the UV region is an attractive feature for the monitoring of membrane proteins.
We manufacture these products so bulk quotations are always available with substantial savings.
Each product is accompanied with a certificate of analysis.
CHAPS references:
1. L.M. Hjelmeland, Proc. Natl. Acad. Sci. USA, 77, 6368 (1980)
2. W.F. Simonds, G. Koski, R.A. Streaty, L.M. Hjelmeland, W.A. Klee, Proc. Natl. Acad. Sci. USA, 77, 4623 (1980)
3. Bitonti, A.J., et al, Biochemistry, 21, 3650 (1982)
4. Rivnay, B., et al, Biochemistry, 21, 6922 (1982)
5. Murayama, T., et al, Biomed. Res., 14, 71 (1993)
6. Caglio, S., et al, Electrophoresis(Weinheim fed. Repub. Ger.), 15, 209 (1994)
7. Hu. W., et al, Anal. Chim. Acta., 285, 335, (9194)
8. Loo, R.R.O., et al, Protein Sci., 3, 1975 (1994)
9. Lundberg, B.J., J. Pharm. Sci., 83, 72 (1994)
10. Radko, S.P., et al, Anal. Biochem., 223, 82 (1994)
11. Wetlaufer, D. B., et al, Protein Sci, 4, 1535 (1995)